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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REST
All Species:
13.64
Human Site:
T430
Identified Species:
37.5
UniProt:
Q13127
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13127
NP_005603.2
1097
121888
T430
S
K
V
K
L
K
K
T
K
K
R
E
A
D
L
Chimpanzee
Pan troglodytes
XP_526617
1314
145077
T647
S
K
V
K
L
K
K
T
K
K
R
E
A
D
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539282
1110
122364
V538
K
T
M
D
V
S
K
V
K
L
K
K
T
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIG1
1082
117822
T425
S
K
V
K
L
K
K
T
K
K
R
E
A
D
L
Rat
Rattus norvegicus
O54963
1069
117108
T429
S
K
V
K
L
K
K
T
K
R
R
E
A
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420580
871
97283
F311
T
H
S
G
E
K
P
F
K
C
D
Q
C
S
Y
Frog
Xenopus laevis
Q2EI21
1501
166152
K428
S
K
V
K
L
R
T
K
K
G
E
V
G
D
E
Zebra Danio
Brachydanio rerio
Q2EI20
855
95544
I295
G
E
R
P
F
Q
C
I
Y
C
E
Y
S
S
S
Tiger Blowfish
Takifugu rubipres
NP_001135958
954
105361
P394
H
V
E
L
H
L
N
P
R
Q
F
L
C
P
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
N.A.
74.9
N.A.
64.7
67
N.A.
N.A.
52.2
36.5
37.2
35.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82.8
N.A.
79.8
N.A.
74.2
76
N.A.
N.A.
62.6
51.2
52.5
50.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
13.3
N.A.
100
93.3
N.A.
N.A.
13.3
46.6
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
40
N.A.
100
100
N.A.
N.A.
26.6
53.3
20
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
45
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
23
0
0
23
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
12
0
0
56
0
% D
% Glu:
0
12
12
0
12
0
0
0
0
0
23
45
0
0
12
% E
% Phe:
0
0
0
0
12
0
0
12
0
0
12
0
0
0
0
% F
% Gly:
12
0
0
12
0
0
0
0
0
12
0
0
12
0
0
% G
% His:
12
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
12
56
0
56
0
56
56
12
78
34
12
12
0
12
12
% K
% Leu:
0
0
0
12
56
12
0
0
0
12
0
12
0
0
45
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
12
12
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
12
0
12
0
0
0
% Q
% Arg:
0
0
12
0
0
12
0
0
12
12
45
0
0
0
0
% R
% Ser:
56
0
12
0
0
12
0
0
0
0
0
0
12
23
12
% S
% Thr:
12
12
0
0
0
0
12
45
0
0
0
0
12
0
0
% T
% Val:
0
12
56
0
12
0
0
12
0
0
0
12
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _